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There have also been mixed success from trials with regards to the utility of TMB. So far, no prospective clinical trials had demonstrated that selection of ICI treatment method determined by a significant TMB in excess of very low TMB improves OS.one,ten Most reports have evaluated TMB in certain tumors varieties, whereas KEYNOTE-158 evaluated TMB
There have also been blended final results from trials with regards to the utility of TMB. To date, no prospective medical trials experienced demonstrated that choice of ICI treatment method based on a substantial TMB about reduced TMB enhances OS.1,10 Most scientific studies have evaluated TMB in unique tumors forms, whereas KEYNOTE-158 evaluated
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